Antibacterial and Antioxidant Activity of Garcinia mangostana Mediated Selenium Induced Nanoparticles: An In vitro Study

Benitha, J. Georgia and Ramani, Pratibha and Rajeshkumar, S. and Gheena, S. and Abhilasha, R. and Reshma, K. (2021) Antibacterial and Antioxidant Activity of Garcinia mangostana Mediated Selenium Induced Nanoparticles: An In vitro Study. Journal of Pharmaceutical Research International, 33 (62A). pp. 490-500. ISSN 2456-9119

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Abstract

Introduction: The biosynthesis of selenium nanoparticles (SeNPs) has gained interest due to their unique chemical and biological properties, which are critical for their possible applications in a variety of fields. Garcinia mangostana (mangosteen) is a tropical fruit known for its edible pulp. The edible pulp accounts for just 30% of the total fruit weight, while the pericarp and seed are discarded. In response to rising public demand for naturally safe foods and items, we conducted a study to determine the antioxidant ability and antibacterial activity of mangosteen pericarp induced with selenium nano particles.

Methods: The antioxidant capacities of selenium nano particles induced mangosteen’s pericarp were determined using 2,2- diphenyl-1-picrylhydrazyl (DPPH) assay, whereas agar well – diffusion technique was used to assess the antibacterial activity on chosen oral pathogens such as Streptococcus mutans, Staphylococcus aureus, Enterococcus faecalis.

Results: In this study, the G. mangostana mediated selenium nanoparticles were synthesized using a green synthesis method. The maximum absorbance of the synthesized selenium nanoparticles was measured using a double beam UV visible spectrophotometer, resulting in a maximum absorbance of 325 nm. The Garcinia mangostana pericarp extract mediated selenium nanoparticles shows potent antimicrobial and antioxidant activity.

Conclusion: The outcomes of our study could facilitate future application of mangosteen waste as a bio preservative in the food industry.

Item Type: Article
Subjects: ScienceOpen Library > Medical Science
Depositing User: Managing Editor
Date Deposited: 18 Feb 2023 12:24
Last Modified: 17 Jun 2024 06:42
URI: http://scholar.researcherseuropeans.com/id/eprint/428

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