Comparative chromatomassspectrometry research of the component composition of fruits and seeds of Chineese Magnolia Vine (Schisándra chinénsis Baill.)

We performed chromatography analysis of alcoholic tincture of fruits and seeds of Chinese Magnolia-Vine ( Schisándra chinénsis Baill.). The fruits and seeds of Chinese Magnolia-Vine ( Fructus Schisandrae and Semina Schisandrae ) is used for herbal drug production. To date there is a pharmacopoeia monograph for the seeds of Chinese Magnolia-Vine. The chromatography analysis made with Agilent Technologies device revealed the major and minor components. The qualitative and quantitative comparison between the tinctures was done with ChemStationE 02.00 software and library for Mass Spectrometry NIST-05. The analysis revealed 14 and 24 substances in the tincture of the fruits and seeds, respectively. We found spirits, acids, sugars, ketons, anthracene derivatives, terpens, ethers etc. We calculated the percentage of each including the unidentified peaks. The study revealed chemical heterogeneity of fruits and seeds of Chinese Magnolia-Vine. The primary components of tinctures were schisandrin and schisandrol. The former is the marker compound which is associated with the pharmacological properties of the drug by many researchers.