Orodispersible Films as a Solution to Drug Acceptability Issues: A Short Review

Yafout, Mohamed and Elhorr, Hicham and Ousaid, Amine and Otmani, Ibrahim Sbai El and Khayati, Youssef (2021) Orodispersible Films as a Solution to Drug Acceptability Issues: A Short Review. Asian Journal of Research in Medical and Pharmaceutical Sciences, 10 (2). pp. 36-41. ISSN 2457-0745

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Abstract

Despite the fact that the tablets are the most widely used dosage form, they are not suitable for young children and patients with swallowing difficulties, especially the elderly. Orodispersible films (ODFs) dissolve rapidly in the mouth and deliver an accurate amount of the active ingredient, which makes them an easy-to-use dosage form that can improve drug acceptability and, therefore, treatment adherence. The findings of the 4 studies that we discussed in this review prove that ODFs have experimentally-proven good acceptability in all age groups and that they are clinically superior to tablets and syrups in terms of acceptability. Therefore, despite some limitations, ODFs are still an innovative and patient-centered dosage form that can contribute to improving drug acceptability and treatment adherence particularly in children and elderly patients. Pharmaceutical companies should focus on developing more ODF-based drugs and also other innovative dosage forms that can make the drug-taking experience even-easier.

Item Type: Article
Subjects: ScienceOpen Library > Medical Science
Depositing User: Managing Editor
Date Deposited: 12 Jan 2023 08:15
Last Modified: 25 Apr 2024 09:02
URI: http://scholar.researcherseuropeans.com/id/eprint/107

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