Ouedraogo, Henri Gautier and Zoure, Abdou Azaque and Sagna, Tani and Soubeiga, Serge Théophile and Compaoré, Tegwinde R and Zingue, Dezemon and Zida, Sylvie and Dabiré, Charlemagne and Kagambega, Alidou and Sawadogo, Charles and Yabre, Zakaria and Sangare, Lassana (2022) Performance of the PanbioTM COVID-19 Ag Rapid Test in a health care setting in Ouagadougou, Burkina Faso. African Journal of Microbiology Research, 16 (11). pp. 334-342. ISSN 1996-0808
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Abstract
This study aimed to evaluate the performance of the PanbioTM Covid-19 Ag Rapid Test (Abbott) in a medical center in Ouagadougou. The PanbioTM COVID-19 Ag test was evaluated from January 26 to March 31, 2021 in symptomatic and asymptomatic patients in the medical Centre of Kossodo. A total of 268 individuals were tested by both SARS-CoV-2 RT-PCR, and antigen RDT. Of these 268 individuals, 52 were positive and 216 were negative for COVID-19 RT-PCR. The performance parameters of the test and its Kappa agreement with the RT-PCR were calculated according to the presence or absence of symptoms in the patients on one hand, and according to the time onset of symptoms on the other hand. The sensitivity of the Panbio™ COVID-19 Ag Rapid Test ranged from 29.63% (95% CI: 13.75 to 50.18) among COVID-19 asymptomatic patients, to 87.5% (95% CI: 52.91 to97.76) among symptomatic patients with symptom onset time of 1-5 days. Similarly, the Panbio™ COVID-19 Ag Rapid Test specificity was 97.3% (95% CI: 90.58 to 99.67) and 96.4% (95% CI: 91.81 to 98.82) in symptomatic and asymptomatic RT PCR negative patients. The Panbio™ COVID-19 Ag Rapid Test shows good performance in detecting COVID-19 cases in patients with a symptom onset time of less than seven (7) days. This performance is even better when the symptom onset is reduced to five (5) days. The results show that the antigen RDT is not suitable for COVID-19 detection among asymptomatic patients.
Item Type: | Article |
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Subjects: | ScienceOpen Library > Biological Science |
Depositing User: | Managing Editor |
Date Deposited: | 27 Mar 2023 06:05 |
Last Modified: | 07 Sep 2024 10:19 |
URI: | http://scholar.researcherseuropeans.com/id/eprint/851 |