Tomita, Masaki and Ayabe, Takanori and Chosa, Eiichi and Nakamura, Kunihide (2014) Five-Year Survivors of Non-Small Cell Lung Cancer Patients with Positive Pleural Lavage Cytology. Advances in Lung Cancer, 03 (01). pp. 21-25. ISSN 2169-2718
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Abstract
Background: The pleural lavage cytology (PLC) for non-small cell lung cancer (NSCLC) patients has been reported as a significant prognostic factor. The aim of this study is to clarify the clinicopathological characteristics of 5-year survivors of patients with positive PLC. Methods: Among 401 resected NSCLC patients, 30 (7.48%) patients with positive PLC were reviewed retrospectively. Results: Only 7 of 30 patients (23.3%) survived more than 5-year. There were no differences in age, gender, histology, pT status and pN status between 5-year survivors and non-survivors. On the other hand, the serum carcinoembryonic antigen (CEA) level was significantly higher in non-survivors. Among these 5-year survivors, 4 of 7 patients died of NSCLC recurrences more than 5 years after surgery. Remaining 3 patients survived without cancer recurrences. Interestingly these 3 survivors had not received any adjuvant therapies after surgery. Conclusion: None of the 5-year survivor with positive PLC had high serum CEA level. Furthermore 5-year survival did not equal to cure in NSCLC patients with positive PLC.
Item Type: | Article |
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Subjects: | ScienceOpen Library > Medical Science |
Depositing User: | Managing Editor |
Date Deposited: | 16 Jan 2023 08:17 |
Last Modified: | 11 Jul 2024 09:32 |
URI: | http://scholar.researcherseuropeans.com/id/eprint/299 |