ASSESSMENT SERUM GLUCOSE AND PLASMA GLUCOSE UNDER IDENTICAL CONDITIONS

According to the International Diabetes Federation, South and Central America region has the proportion of 41.9% people with diabetes who are undiagnosed. Several factors influence the stability of glucose values after collection as “in vitro” glycolysis. Aim of this study was to compare the fasting glucose levels either in plasma or in serum under identical conditions.

Methodology: Blood samples were collected in K2 EDTA and serum tubes with clot activator and both tubes were maintained in upright position for 30 min at room temperature to allow clot formation. Also, linear regression model was used for evaluate la relationship between glucose plasma and glucose serum and multiple linear regression was used and two model for obtain coefficients adjusted by hematology parameters covariates.

Results: Mean glucose in serum tube was -1.57 mg/dl than K2 EDTA tube and that was no statistically significant difference for glucose (p = 0.41) and neither clinically significant. But on the other hand, serum glucose increases by 1 mg/dl; while EDTA glucose increases by an average of 0.59 mg/dl (p<0.05).

Conclusion: Serum glucose is similar to plasma glucose when hematology parameters between the reference range.